ZNF43
From Wikipedia, the free encyclopedia
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Zinc finger protein 43
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| Identifiers | ||||||||||||||
| Symbol(s) | ZNF43; AURKA; ARK1; AURORA2; BTAK; STK15; KOX27; DKFZp686L1854; HTF6; ZNF39L1 | |||||||||||||
| External IDs | OMIM: 603972 MGI: 3040691 HomoloGene: 86693 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 7594 | 238690 | ||||||||||||
| Ensembl | ENSG00000198521 | ENSMUSG00000055480 | ||||||||||||
| Uniprot | P17038 | n/a | ||||||||||||
| Refseq | NM_003423 (mRNA) NP_003414 (protein) |
NM_001001152 (mRNA) NP_001001152 (protein) |
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| Location | Chr 19: 21.78 - 21.81 Mb | Chr 13: 67.76 - 67.76 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Zinc finger protein 43, also known as ZNF43, is a human gene.[1]
This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Lovering R, Trowsdale J (1991). "A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines.". Nucleic Acids Res. 19 (11): 2921–8. PMID 1711675.
- Huebner K, Druck T, Croce CM, Thiesen HJ (1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.". Am. J. Hum. Genet. 48 (4): 726–40. PMID 2014798.
- Bellefroid EJ, Poncelet DA, Lecocq PJ, et al. (1991). "The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.". Proc. Natl. Acad. Sci. U.S.A. 88 (9): 3608–12. PMID 2023909.
- Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells.". New Biol. 2 (4): 363–74. PMID 2288909.
- Bellefroid EJ, Marine JC, Ried T, et al. (1993). "Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.". EMBO J. 12 (4): 1363–74. PMID 8467795.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:. PMID 11256614.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:. PMID 15489334.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:. PMID 15489336.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:. PMID 16381901.
- Takahashi T, Furuchi T, Naganuma A (2007). "Endocytic Ark/Prk kinases play a critical role in adriamycin resistance in both yeast and mammalian cells.". Cancer Res. 66 (24): 11932–7. doi:. PMID 17178891.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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