ZBTB7B
From Wikipedia, the free encyclopedia
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Zinc finger and BTB domain containing 7B
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| Identifiers | ||||||||||||||
| Symbol(s) | ZBTB7B; DKFZp686G01254; ZBTB15; ZFP67; c-Krox; hcKrox | |||||||||||||
| External IDs | OMIM: 607646 MGI: 102755 HomoloGene: 7605 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 51043 | 22724 | ||||||||||||
| Ensembl | ENSG00000160685 | ENSMUSG00000028042 | ||||||||||||
| Uniprot | O15156 | Q5BJ24 | ||||||||||||
| Refseq | NM_015872 (mRNA) NP_056956 (protein) |
XM_988936 (mRNA) XP_994030 (protein) |
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| Location | Chr 1: 153.24 - 153.26 Mb | Chr 3: 89.46 - 89.48 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Zinc finger and BTB domain containing 7B, also known as ZBTB7B, is a human gene.[1]
ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.[supplied by OMIM][1]
[edit] References
[edit] Further reading
- Galéra P, Musso M, Ducy P, Karsenty G (1994). "c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin.". Proc. Natl. Acad. Sci. U.S.A. 91 (20): 9372-6. PMID 7937772.
- Widom RL, Culic I, Lee JY, Korn JH (1997). "Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression.". Gene 198 (1-2): 407-20. PMID 9370309.
- Heegaard AM, Gehron Robey P, Vogel W, et al. (1998). "Functional characterization of the human biglycan 5'-flanking DNA and binding of the transcription factor c-Krox.". J. Bone Miner. Res. 12 (12): 2050-60. PMID 9421237.
- Ghayor C, Herrouin JF, Chadjichristos C, et al. (2000). "Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration.". J. Biol. Chem. 275 (35): 27421-38. doi:. PMID 10856292.
- Widom RL, Lee JY, Joseph C, et al. (2002). "The hcKrox gene family regulates multiple extracellular matrix genes.". Matrix Biol. 20 (7): 451-62. PMID 11691585.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:. PMID 16189514.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:. PMID 16710414.
- Kypriotou M, Beauchef G, Chadjichristos C, et al. (2007). "Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors.". J. Biol. Chem. 282 (44): 32000-14. doi:. PMID 17698844.

