ZBTB7B

From Wikipedia, the free encyclopedia


Zinc finger and BTB domain containing 7B
Identifiers
Symbol(s) ZBTB7B; DKFZp686G01254; ZBTB15; ZFP67; c-Krox; hcKrox
External IDs OMIM: 607646 MGI102755 HomoloGene7605
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 51043 22724
Ensembl ENSG00000160685 ENSMUSG00000028042
Uniprot O15156 Q5BJ24
Refseq NM_015872 (mRNA)
NP_056956 (protein)
XM_988936 (mRNA)
XP_994030 (protein)
Location Chr 1: 153.24 - 153.26 Mb Chr 3: 89.46 - 89.48 Mb
Pubmed search [1] [2]

Zinc finger and BTB domain containing 7B, also known as ZBTB7B, is a human gene.[1]

ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.[supplied by OMIM][1]

[edit] References

[edit] Further reading

  • Galéra P, Musso M, Ducy P, Karsenty G (1994). "c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin.". Proc. Natl. Acad. Sci. U.S.A. 91 (20): 9372-6. PMID 7937772. 
  • Widom RL, Culic I, Lee JY, Korn JH (1997). "Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression.". Gene 198 (1-2): 407-20. PMID 9370309. 
  • Heegaard AM, Gehron Robey P, Vogel W, et al. (1998). "Functional characterization of the human biglycan 5'-flanking DNA and binding of the transcription factor c-Krox.". J. Bone Miner. Res. 12 (12): 2050-60. PMID 9421237. 
  • Ghayor C, Herrouin JF, Chadjichristos C, et al. (2000). "Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration.". J. Biol. Chem. 275 (35): 27421-38. doi:10.1074/jbc.M002139200. PMID 10856292. 
  • Widom RL, Lee JY, Joseph C, et al. (2002). "The hcKrox gene family regulates multiple extracellular matrix genes.". Matrix Biol. 20 (7): 451-62. PMID 11691585. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414. 
  • Kypriotou M, Beauchef G, Chadjichristos C, et al. (2007). "Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors.". J. Biol. Chem. 282 (44): 32000-14. doi:10.1074/jbc.M705197200. PMID 17698844.